AbbVie to Acquire Gilgamesh’s Bretisilocin in $1.2B Psychedelic Bet

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From Collaboration to Acquisition

The acquisition builds on a partnership established in 2024, when AbbVie and Gilgamesh entered into an option-to-license agreement to explore next-gen psychiatric therapies. That agreement will now transfer to the newly spun-off Gilgamesh Pharma, ensuring continuity in both research and collaboration.

Gilgamesh CEO Jonathan Sporn hailed the deal as transformative:

“AbbVie’s leadership in neuroscience makes them the ideal partner to accelerate bretisilocin’s development, while Gilgamesh can continue advancing its mission of delivering groundbreaking therapies for complex mental health and neurological conditions.”

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Legal Advisors Behind the Deal

  • AbbVie: Advised by Covington & Burling LLP, with partners Catherine Dargan and Kyle Rabe leading the team.

  • Gilgamesh: Represented by Ropes & Gray LLP, with life sciences partner Hannah England and M&A partner Matt Byron steering the transaction.

This acquisition, blending pharmaceutical innovation with psychedelic science, underscores how far Big Pharma is willing to go in the race to conquer treatment-resistant depression—staking billions on a future where mental health care may look very different from today.